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    Sertraline
    Clinical data
    Trade namesZoloft and others [1]
    AHFS/Drugs.comMonograph
    MedlinePlusa697048
    Pregnancy categoryAU: C US: C (Risk not ruled out)
    Routes of administrationBy mouth (tablets and solution)
    Drug classSelective serotonin reuptake inhibitor
    ATC codeN06AB06 ( WHO )
    Legal status
    Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
    Bioavailability44%
    Protein binding98.5%
    MetabolismHepatic ( N -demethylation mainly by CYP2B6) [2]
    Elimination half-life~23–26 h (66 h [less-active [3] metabolite, norsertraline]) [4]
    ExcretionRenal

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