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    Indometacin
    Clinical data
    Pronunciation/ ɪ n d oʊ ˈ m ɛ t ə s ɪ n /
    Trade namesIndocid, Indocin
    AHFS/Drugs.comMonograph
    License dataUS   FDA: Indomethacin
    Pregnancy categoryAU: C C/D (US)
    Routes of administrationOral, rectal, IV, topical
    ATC codeC01EB03 ( WHO ) M01AB01 ( WHO ), M02AA23 ( WHO ), S01BC01 ( WHO )
    Legal status
    Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
    Bioavailability~100% (oral), 80–90% (rectal)
    Protein binding99% [1]
    MetabolismHepatic
    Elimination half-life2.6-11.2 hours (adults), 12-28 hours (infants) [1]
    ExcretionRenal (60%), fecal (33%)

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